Showing posts with label cancer. Show all posts
Showing posts with label cancer. Show all posts

Monday, 9 February 2015

Warning Signs of Cancer

"One in two people will develop cancer over the course of their lives, according to a new report from Cancer Research UK."

This number is creeping higher than past estimates, which have often cited a one-in-three figure. According to the new study published in the British Journal of Cancer, the odds of getting cancer over the course of one’s life jumped from 38.5 percent for men born in 1930 to 53.5 percent for men born in 1960. The hike was from 36.7 percent
to 47.5 percent in women.

According to the American Cancer Society, the United States has very similar figures. Although health care is actually improving — in the UK, for instance, researchers note the cancer survival rate has doubled over the past 40 years — there’s an uptick in disease incidence because of the aging population. 

“Cancer is primarily a disease of old age, with more than 60 percent of all cases diagnosed in people aged over 65,” says study author Peter Sesieni, a professor of Biostatistics & Cancer Epidemiology and Deputy Director of the Centre for Cancer Prevention at Queen Mary University of London, in a statement. “If people live long enough then most will get cancer at some point.” 


This, the researchers say, is why education on cancer prevention is so necessary. “There’s a lot we can do to make it less likely — like giving up smoking, being more active, drinking less alcohol and maintaining a healthy weight,” Sesieni says. “If we want to reduce the risk of developing the disease we must redouble our efforts and take action now to better prevent the disease for future generations.”

Most experts also agree that spotting the disease early gives a person the best chance of beating it. However, many blow off symptoms as bodily quirks — and some may well be, but it’s best to talk to a doctor if there’s an unexplained issue. 

According to Cancer Research UK, which conducted the latest study, these are the most common signs of cancer:

Signs of cancer for men and women:
  1. An unusual lump or swelling anywhere on your body
  2. A change in the size, shape or colour of a mole
  3. A sore that won’t heal after several weeks
  4. A mouth or tongue ulcer that lasts longer than three weeks
  5. A cough or croaky voice that lasts longer than three weeks
  6. Persistent difficulty swallowing or indigestion
  7. Problems passing urine
  8. Blood in your urine
  9. Blood in your bowel motions
  10. A change to more frequent bowel motions that lasts longer than four to six weeks
  11. Unexplained weight loss or heavy night sweats
  12. An unexplained pain or ache that lasts longer than four weeks
  13. Breathlessness
  14. Coughing up blood
Signs of cancer for women:
  1. An unusual breast change
  2. Bleeding from the vagina after the menopause or between periods
  3. Persistent bloating
Now, remember: This news should not cause mass panic, according to the UK’s Chief Medical Officer Dame Sally Davies. People are living longer, which is why we’re seeing more cancer. “Cancer survival rates have improved to record levels in this country and we are working to raise awareness of cancer symptoms so it can be diagnosed earlier, improving cancer outcomes,” she says in the press release. “Leading a healthy lifestyle is easily the most effective thing you can do to reduce your risk, this means being active, quitting smoking, drinking less alcohol, and having a balanced diet.”

Original Post Found Here:
https://www.yahoo.com/health/17-red-flag-signs-of-cancer-110161560812.html

Thursday, 1 January 2015

The New Health Threats You'll Be Seeing In 2015

The New Health Threats You'll Be Seeing In 2015

Don’t let these new health enemies threaten you in 2015. (James Brey/Getty Images) 

There are the health woes we worry about year after year — think obesity, diabetes, and opioid addiction — and then there are the ones that threaten to catch us off guard. We’re talking about the public health enemies that emerge with sudden, unexpected force — and then leave us all wondering why we didn’t see them coming.


This year, it was Ebola, the deadly virus responsible for thousands of lives lost in West Africa. “Ebola has gotten most of the attention this year,” says Scott Weaver, director of the Institute for Human Infections and Immunity at the University of Texas. Yet, despite fears of a stateside epidemic, the virus never invaded U.S. borders in serious numbers — and it’s not likely to do so in 2015, he says, even as the war against Ebola in West Africa rages on.


But there are other viruses — some familiar, some not — that are poised for attack on U.S. soil in the coming year, whether we’re ready or not. And it’s just not infectious invaders we have to worry about, either — there are also a handful of homegrown health foes, ranging from fracking to inferior health insurance, threatening to tighten their grip in 2015.


CHIKUNGUNYA VIRUS 

image Mosquitos may just seem like pests, but they could actually be carrying a debilitating virus. (BSIP/UIG/Getty Images)

The chikungunya virus may have a funny-sounding name, but it’s nothing to laugh about. So far, all but four states in the U.S. have reported cases of chikungunya — and the mosquito-borne virus’s foothold will only increase in 2015, says Weaver. As chikungunya spreads from the Caribbean to Central and South America, “I suspect the number of cases may increase, because the virus is going to be circulating in a much larger area, with much larger populations,” he says. “I think it’s inevitably going to spread up through Mexico to the U.S. border.”


Chikungunya made tabloid headlines this week when actress Lindsay Lohan contracted the virus while vacationing in French Polynesia. "Being sick is no fun," Lohan tweeted. "But happy new year everyone. Be safe." And she shared an important lesson learned from her experience: use bug spray.
An under-the-weather Lohan with pals in French Polynesia. (Photo: Instagram)

And trust us, this is one virus you definitely don’t want to catch: Chikungunya causes debilitating, arthritis-like pain that can last for years, says Weaver. 

Right now, chikungunya — which has no known cure — is primarily transmitted through the Aedes aegypti mosquito, found only in the southern United States. However, another strain recently emerged in Brazil that may favor the Aedes albopictus mosquito, which “can survive further north in the temperate areas of the U.S.,” says Weaver. “It can survive cold winters. So if that strain is imported in travelers, it could be a risk almost anywhere in the eastern half of the U.S., where Aedes albopictus is present.”

Chikungunya can’t spread from person to person — a mosquito go-between is necessary — so you’re currently most likely to catch it while traveling in the Caribbean, Central America, or South America. “You really have to cover up your skin, either with clothing or repellant, and worry about being bitten all day long,” Weaver says.

Unlike most mosquitos that pester us in the States, Aedes aegypti is primarily a daytime biter — and it will come indoors, especially where there’s no central air or window screens. “You can’t simply assume that when you’re inside you’re protected,” says Weaver. 

Another virus to keep your eye on: dengue. Although it’s not yet a major concern in the United States, the United Nations recently issued a warning about potential outbreaks of the deadly virus in Europe, West and Central Africa, and South America.


HIGH-DEDUCTIBLE HEALTH PLANS

 image
Tempted to choose a high-deductible plan? Your health may take a hit if you do. (Image Source/Getty Images)

Under the Affordable Care Act (ACA), we’re all required to have health insurance — but that doesn’t mean we’ll all end up with quality coverage, even if our employers are providing the plans. Nearly a third of large employers plan to offer only high-deductible plans in 2015, up from 22 percent in 2014, according to the National Business Group on Health. “There’s been a very powerful trend toward greater patient cost sharing in health insurance plans,” says Paul Ginsburg, a professor at the University of Southern California’s Schaeffer Center for Health Policy & Economics.

In fact, according to a new American Health Policy Institute report, “Although employers will continue to pick up the large majority of employee health care costs, employee deductibles, copayments, and out-of-pocket maximums will continue to increase.” Starting in 2015, high-deductible plans can require out-of-pocket spending of up to $6,450 for a single person and $12,900 for a family.

Why the shift toward such high deductibles? For a long time, the cost of health insurance has been rising more rapidly than our incomes, so companies are increasingly turning to high-deductible plans to keep employee premiums down, says Ginsburg.

However, there may also be a less benign financial motive: In 2018, the ACA’s so-called Cadillac tax will go into effect, forcing companies to pay a 40 percent excise tax on employee health coverage beyond $10,200 for an individual or $27,500 for a family. In preparation, some employers are switching to high-deductible, low-premium plans to avoid being hit with the tax, says Ginsburg.

It’s not just to your pocketbook that high-deductible plans pose a threat. “Many insurance companies and employers see deductibles as a way to keep the use of health care services down,” says Sabrina Corlette, a senior research fellow at Georgetown University’s Center on Health Insurance Reforms. “When consumers have to pay that upfront cost for their health care, they may be a little more reluctant to get it. These plans can cause people to delay or forgo care that they actually need.”

Although the ACA requires free coverage of many preventive services, high-deductible plans may discourage management of chronic disease — for example, if a patient needs frequent doctor visits and monthly prescriptions, but has to pay the costs out of pocket, he or she may decide to opt out of necessary care, says Ginsburg.

His advice: If you can’t easily obtain the cash to cover your full deductible in case of an emergency, pick a higher-premium, lower-deductible plan. Likewise, if you need health care throughout the year — say, you have a condition that requires monthly check-ups — you may want to consider a lower-deductible option, says Corlette.

INFLUENZA

 image
This year’s flu vaccine isn’t as effective as hoped, which means the season may be especially severe. (Mehmed Zelkovic/Getty Images)
 
Although this flu season isn’t poised to be a repeat of the 2009-2010 H1N1 pandemic, early data does suggest that this year could be severe, according to the Centers for Disease Control and Prevention. So far, H3N2 viruses have dominated the season, and in the past, when this strain has emerged as the primary threat, death rates have been unusually high, the CDC says.

What makes this especially worrisome: The circulating strain of H3N2 has mutated, so this year’s vaccine is protective in only about half of cases. “The flu vaccine that’s developed each year is based on educated guesses that take place long before the transmission season begins,” says Weaver. “Unfortunately, one of the strains that is circulating fairly widely was not included in the formulation that was developed.”

Blame it on a phenomenon called “antigenic drift,” where the influenza virus mutates so it can infect more people. “The virus is constantly changing,” Weaver says. “If you were infected with H3N2 a few years ago, the strain circulating this year may overcome that immunity, and you can become reinfected with that strain.”
Still, the CDC strongly recommends vaccination, since it will protect against the other circulating strains of the flu. And even if you do get sick, your infection may be milder if you’ve been vaccinated.


E-CIGARETTES 

 image
Although not as chemical-laden as traditional cigs, E-cigarettes aren’t entirely benign, either. (Martina Paraninfi/Getty Images)

For the first time, U.S. teens are experimenting with E-cigarettes at a higher rate than traditional cigs, according to a new national study from the University of Michigan. And the uptick in E-cigarette use — in both teens and adults — is only going to continue in the coming year, predicts James Sargent, M.D., a professor of pediatrics and co-director of the Cancer Control Research Program at Dartmouth University. Since the marketing of E-cigarettes is largely unregulated, “there’s nothing out there to stop [the upward trend],” he says. “They’re on television. They’re all over the place. And people are curious.”

Although many would argue that E-cigarettes are preferable to the real deal, they’re not without risk: A 2014 UC San Francisco study found that teens who “vape” are nearly eight times more likely to smoke cigarettes than those who don’t use E-cigs. “The concern is that children will get addicted to nicotine by using E-cigarettes, and then they’ll realize they can get nicotine a lot more efficiently through cigarettes,” says Sargent. Similarly, former adult smokers might reawaken their nicotine addiction by using E-cigarettes, and then end up relying on both products.

Another fear: Adult smokers may take up E-cigarettes to help them quit, but ultimately end up being “dual users” — that is, puffing on both E-cigarettes and traditional cigs. In another 2014 UC San Francisco study, vaping wasn’t associated with a change in cigarette consumption, suggesting that the smoke-free devices may not be as useful for kicking the habit as hoped (although research here is conflicting). “The concern is that being able to use E-cigarettes will just prolong smokers’ use of cigarettes,” since it can offset some of the cost of cigarettes or allow them to dose up on nicotine in places were cigs are prohibited, says Sargent.

 FRACKING

 image
Fracking may elevate levels of methane in drinking water — one of several ways it could threaten human health. (Mark Thiessen/Corbis)

As fracking — an oil-drilling method that injects high-pressure water and chemicals below the earth’s surface — continues to gain ground, American support for it is on the decline: In a new Pew Research Center survey, 47 percent of Americans said they’re against the increased use of fracking, versus 38 percent in 2013. This rising tide of opposition is reflected in New York Governor Andrew Cuomo’s recent ban on fracking in the Empire State, which he announced after the state released a public health analysis of the practice.

Even so, “fracking isn’t going away,” says Susan Nagel, a reproductive health expert at the University of Missouri, who has studied chemicals used in fracking. “It’s very, very entrenched in many states.” Part of the problem, she admits, is the lack of human health data on fracking. But the studies that are available have shown alarming effects. A 2014 Environmental Health Perspectives study, for example, found that pregnant women who live near fracking sites are more likely to have children with congenital heart defects and, possibly, neural tube defects.

Research also suggests a link between fracking and reduced sperm count, potentially because of the chemicals that the drilling method requires. “They’re being liberated into the air throughout the process,” says Nagel. “And then, through disposal of the wastewater, they contaminate surface water and potentially groundwater.” 

About a third of the chemicals used are endocrine disruptors — specifically, “many of them are anti-androgens,” she says. “So they oppose the action of normal male sex hormones, like testosterone. Androgens are needed for normal sperm development. Exposure to anti-androgens can inhibit that entire process.”

It’s unknown how close you have to live to fracking zones in order to see these potential health effects. “There are certainly millions of people in this country that live in the thick of drilling areas,” says Nagel. “Right now, we don’t know how close you have to live — that is the concern.”



SYNTHETIC MARIJUANA

 image
Synthetic marijuana is now illegal, but its use doesn’t seem to be slowing down. (The Washington Post/Contributor/Getty Images)

What looks like potpourri is actually a drug more potent than marijuana. Often referred to simply as “Spice,” synthetic cannabinoids — of which there are hundreds of varieties — are considered Schedule I substances, officially making it illegal to sell them in convenience stores, where they initially began cropping up a few years back.

“The problem is, we are continuing to see people in very high numbers [who are] psychotic, after having used synthetic cannabinoids,” says Stephen Ross, M.D., director of addiction psychiatry at NYU Tisch Hospital. When asked where they acquired the drugs, “they say the local bodega or deli — it’s like $6, and it’s super potent,” he says. “Synthetic cannabinoids are still very available.”

In August 2014, New Hampshire Governor Maggie Hassan declared a public health emergency in response to the state’s high number of Spice overdoses. Other states are seeing an uptick in poison-control calls about the drug. “In 2013, we had zero calls to the Poison Center about it. So far to date in 2014, we’ve had 133 calls about synthetic marijuana,” Lee Livermore, the public health educator for the Upstate New York Poison Center, told Time Warner Cable News. This past summer, nearly 120 people in Dallas and Austin overdosed on the drug in a five-day period.

With synthetic marijuana, “we see cardiac toxicity. We’ve seen some renal toxicity,” says Ross. “There are even some deaths associated with [the drug].” 

What makes synthetic cannabinoids so potent?

Marijuana contains two primary compounds: THC and cannabidiol. THC — the component known for getting people high — binds to cannabinoid-1 receptors, which are responsible for the addictive, anxiety-inducing effects of marijuana. “THC from cannabis smoke is only a partial activator of that receptor — it’s what’s known as a ‘partial agonist,’” Ross says. “But synthetic cannabinoids are a full agonist of that receptor.”

Plus, the cannabidiol in marijuana has the opposite effect of THC — it’s calming — so “it tempers the negative psychiatric effects of activation of the cannabinoid-1 receptor,” says Ross. Synthetic cannabinoids don’t have that advantage. “They only have the [compound] that causes addiction, anxiety, and psychosis.”


WHOOPING COUGH

 image
The long-gone disease is making a comeback, with rates at a 70-year high. (Photo: The Image Bank/Getty Images)
You probably lump whooping cough, or pertussis, in with diseases of yesteryear, like Scarlet fever and the measles. But the truth is, the respiratory ailment is making a killer comeback—in fact, California is in the midst of a whooping cough epidemic, with rates at a 70-year high. As of late November, nearly 10,000 cases, primarily in children, had been reported in the state, according to the California Department of Public Health. It’s not just the West Coast that’s suffering, either: From January to mid-August of 2014 alone, there were more than 17,000 pertussis cases in the U.S.—a 30 percent increase over the same time period in 2013, according to the CDC.
 
And the outlook for 2015 isn’t any better. “I think we’re going to continue to have pretty substantial pertussis in the United States in 2015,” says Arthur Reingold, M.D., head of epidemiology at the Berkeley School of Public Health. Why? Across the U.S., particularly in wealthier areas, parents are opting not to vaccinate their little ones, he says, and even if they do, the current vaccine doesn’t offer lifetime protection. In the 1990s, U.S. practitioners switched from the whole-cell pertussis vaccine to the acellular one, “because the old vaccine produced more fever, pain, and tenderness,” explains Reingold. Problem is, the new version wears off after a few years, leaving children vulnerable to whooping cough.
 
When the bacteria that causes the cough is actively circulating, infants are at risk of being infected by non-vaccinated family members or those with waning immunity—and the outcome can be deadly. “In the first few months of life, whooping cough can be life threatening,” Reingold says. “Even if infants get their first dose of vaccine when they’re supposed to—at 2 months of age—they’re not fully protected until they’ve had several doses.” 
 
That’s why the CDC recommends vaccinating pregnant women (the mother’s immunity is passed along to her baby), as well as any other family members who’ll be around the newborn. “It’s called cocooning—trying to vaccinate all the other people in the household around the young baby,” Reingold says. And parents should make sure their children receive the full schedule of vaccines for maximum protection, he adds.


Original Post Found Here:

Is Cancer Risk Mostly Affected By Genes, Lifestyle Choices, Or Just Plain Bad Luck?

Is Cancer Risk Mostly Affected By Genes, Lifestyle Choices, Or Just Plain Bad Luck?

Experts say the findings highlight “the importance of secondary prevention, like early detection.” (Photo: Getty Images)


While cancer can strike anyone — young or old, unhealthy and healthy — we do have some idea of what can affect risk. Genetics often play a role, for instance, as do lifestyle habits. But according to a new study from Johns Hopkins University researchers, much of cancer risk may actually be due to mere chance.


Cancer develops when stem cells of a given tissue make random mistakes, mutating unchecked after one chemical letter of DNA is incorrectly swapped for another — the equivalent of a cell “oops.” It happens without warning, like the body’s roll of the die. 


For the new study, published in the journal Science, researchers wanted to see how much of overall cancer risk was due to these unpreventable random mutations, independent of other factors like heredity and lifestyle. 


“There is this question that is fundamental in cancer research: How much of cancer is due to environmental factors, and how much is due to inherited factors?” Cristian Tomasetti, Ph.D., a biomathematician and assistant professor of oncology at the Johns Hopkins University School of Medicine and Bloomberg School of Public Health, tells Yahoo Health. “To answer that question, however, the idea came that it would be important to determine first how much of cancer was simply due to ‘replicative chance.’”




To measure this, the researchers plotted the number of stem cell divisions in 31 types of tissues over the course of a lifetime against the lifetime risk of developing cancer in the given tissue. From the chart, the scientists were able to see the correlation between number of divisions and cancer risk — and from that correlation, researchers were able to determine the incidence of cancer in a given tissue due to replicative chance.


Ultimately, researchers found that roughly two-thirds of the cancers were due to this replicative chance. (However, it’s worth noting researchers did not examine some cancers, such as breast and prostate cancers, because of lack of reliable stem-cell turnover information.)


But don’t assume you’re simply doomed to the hand fate deals you. After additional analysis, researchers found that of the 31 cancers examined, 22 could be explained by “bad luck” — but for the other nine, there was another factor aside from simple chance that likely contributed to the cancer.


This is presumably because environmental and hereditary factors play a role in development. “There are many cancers where primary prevention has huge positive effects, such as vaccines against infectious agents, quitting smoking or other altered lifestyles,” says Tomasetti. 



Incidentally, the cancers where risk could be lowered by primary preventive practices were ones you may expect — diseases like skin cancer, where limiting sun exposure can lower your risk, as well as lung cancer, where avoiding smoking is key. 


While the study shows that for many cancers, primary prevention — such as adopting healthy lifestyle habits — may not fully work to keep from developing cancer, this “does not imply at all that there is not much we can do to prevent those cancers,” Tomasetti says. “It just highlights the importance of secondary prevention, like early detection.”

Since so much of risk is based on random cell division, identifying a mutation before replication goes unchecked throughout the body is, and will continue to be, essential. “It is still fundamental to do what we can in terms of primary prevention to avoid getting cancer, but now we understand better what causes cancer and how relevant the ‘bad luck’ component is, because we have a measure of it,” Tomasetti explains. “This work tells us that randomness plays an important role in cancer, possibly much larger than previously thought. And therefore early detection becomes even more important.”


You can also look at this new research another way, though, according to Tomasetti. “On one side, it actually strengthens the importance at the individual level to avoid risky lifestyles,” he explains. “If my parents smoked all their lives and did not get lung cancer, it is probably not because of good genes in the family, but simply because they were very lucky. 

“I would be playing a very dangerous game by smoking,” Tomasetti says. See? Healthy habits do count.