Showing posts with label Alzheimer’s disease. Show all posts
Showing posts with label Alzheimer’s disease. Show all posts

Thursday, 1 January 2015

Fish Oil Boosts Brain Power

Fish Oil Boosts Brain Power

Photo by Getty Images


Fish oil is touted as a magical potion that boosts fertility, heart health, and weight loss and promotes a clear complexion, while lessening the effects of depression, ulcers, diabetes and many more conditions. But there’s another benefit to these glossy little capsules: They may prevent Alzheimer’s disease. 


A new study of 819 people published in the journal Alzheimer’s & Dementia found that taking fish oil supplements on a daily basis is associated with a significant decrease in cognitive decline (as measured by the Alzheimer’s Disease Assessment Scale and the Mini Mental State Exam) and brain atrophy — important findings in light of statistics that show that one person per minute is diagnosed with Alzheimer’s disease. 


“We found that fish oil use was associated with better performance on standard tests of memory and thinking abilities over time, compared to those who didn’t take supplements,” lead study author Lori Daiello, a research scientist at the Alzheimer’s Disease and Memory Disorders Center at Rhode Island Hospital, tells Yahoo Health. “They also experienced less brain shrinkage in areas of the brain important for healthy cognitive aging — the cerebral cortex and hippocampus, the portion of the brain responsible for forming and retaining memories.” 


For this study, researchers analyzed information from neuropsychological tests and MRI brain imaging performed at regular intervals for up to four years during the Alzheimer’s disease Neuroimaging Initiative, a longitudinal study of brain aging and Alzheimer’s Disease. The population consisted of a group of older adults with varying degrees of cognitive capability: normal cognitive function, mild cognitive impairment, and Alzheimer’s disease. The benefit of fish oil appeared strongest in the group with normal cognitive functioning. “Retrospective studies cannot establish cause and effect, so we can’t make a global recommendation that everyone should start taking fish oil supplements. But the findings highlight the need for additional research on the effects of longterm fish oil use on brain health in later life,” says Daiello.  


The main ingredient in fish oil is DHA, omega-3 fatty acids found in cold-water fatty fish such as salmon, swordfish, trout, yellow fin tuna, mackerel, and more. (Non fish-lovers can find it in eggs, milk, and algae-derived supplements). 

According to Daiello, there is no definitive evidence that eating fish daily is better than taking fish-oil supplements. But some people dislike the fishy breath that lingers after taking the supplements. “In that case, you could always store the capsules in the freezer, which seems to diminish the scent,” suggests Daiello. (Though the study did not address the dosage of daily fish oil to take, the World Health Organization recommends a daily EPA and DHA intake of 0.3 to 0.5 grams and a daily ALA intake of 0.8 to 1.1 grams.)


And while the effects of fish oil have been well-documented, they also carry a “buyer beware” element. One study, conducted by a testing company called LabDoor, found that what’s advertised on the label of many supplements may not live up to their promise of what’s advertised on the labels. When the company analyzed 30 top-selling brands, they found that six products exaggerated the amount of omega-3 on their labels by 30 percent. And at least a dozen products contained DHA levels that were 14 percent less than advertised. “Mislabeling is a big problem because the FDA considers fish oil supplements food, not drugs, so they aren’t regulated,” says Daiello. “So it’s tough to verify the purity of what you buy.” 
To select the best supplement, talk to your doctor, who may be able to recommend a pill that’s right for your needs. Or join a subscription-based website such as Consumer Lab, which regularly tests vitamins and supplements. 

5 Ways to Lower Your Risk for Alzheimer's Disease

5 Ways to Lower Your Risk for Alzheimer's Disease
New research suggests aluminum exposure contributes to dementia, but there is plenty you can do to lower your risk. 
Photo: Getty Images

Aluminum is one of the most widely used metals in the world. Consider your morning commute: You hop into your car, where you’re protected from the elements by aluminum body panels. You sip your morning coffee from an aluminum travel mug. You arrive at your desk and pry open your laptop’s aluminum case to check your email.

All of this exposure to aluminum, however, may come at a cost. Research suggests that the metal — a known neurotoxin — builds up in the brain over time, contributing to Alzheimer’s disease and other neurodegenerative conditions.

Writing in a recent issue of The Lancet, neuroscientist Chris Exley made an impassioned case that the modern Aluminum Age, as he calls it, plays a significant role in neurodegenerative diseases. We overlook these risks because aluminum is so common, Exley argued. But there are several explanations for how aluminum may contribute to Alzheimer’s disease. For one, aluminum encourages proteins called amyloids to clump together in the brain, which is a key feature of Alzheimer’s disease. This accumulation may block signals between nerve cells or lead to changes that destroy brain cells.

Aluminum is toxic to the brain, just like mercury, lead, and arsenic, said neurologist David Perlmutter, MD, author of Grain Brain and the Grain Brain Cookbook, in an interview with Yahoo Health. “Over the past 20 years there have been several important research publications that have drawn conclusions relating Alzheimer’s disease to aluminum exposure,” he added. Studies have linked higher aluminum content in drinking water to higher rates of Alzheimer’s disease, for example. And one of the most promising Alzheimer’s therapies involves removing aluminum from the body, providing evidence that the two are closely connected, according to a research review in Frontiers in Aging Neuroscience.


Five Tips to Keep Your Brain Sharp
Because aluminum is so pervasive, it’s nearly impossible to avoid completely. But taking certain steps can significantly lower your risk of developing dementia. “The truth of the matter is that there is no treatment for dementia now or at any time in the foreseeable future, and yet dementia, for the most part, is strongly related to lifestyle choices such as diet, exercise, and even preventing head trauma,” said Perlmutter. “This is powerful information as it puts dementia into the same category as heart disease, for example, in which everyone seems to be very aware of the fact that there are things we can do to prevent that issue.”

If you’re looking to keep your dome healthy, lowering your exposure to aluminum is one course of action, but it’s not the most important one. “These studies on aluminum are intriguing but are in no way as significant as other important and modifiable risk factors for Alzheimer’s disease for which there is profound support in the medical literature,” Perlmutter said.

Follow these tips to reduce your risk for dementia and keep your brain healthy as you age:
1) Watch your blood sugar. “Even mild elevations of blood sugar, well below the threshold for making a diagnosis of diabetes, have now been demonstrated to significantly correlate with the risk of developing dementia,” said Perlmutter. To keep blood sugar under control, limit the amount of carbohydrates you consume and choose healthy fats such as olive oil, coconut oil, nuts, and seeds. If you choose to eat meat, pick grass-fed beef and wild fish, which are higher in heart-healthy omega-3 fatty acids.

2) Keep up with cardio. “Physical activity is a wonderful brain activity,” Douglas Scharre, MD, director of the division of cognitive neurology at Ohio State University, told Yahoo Health. Aerobic activity can make your brain more resilient against developing dementia, studies suggest. Perlmutter recommended at least 20 minutes of sustained aerobic activity each day, such as running, brisk walking, or bike riding. 

3) Protect your noggin. Even mild head trauma early in life — a hard knock during a high school football game or a rough crash while rollerblading — can set the stage for dementia later on, Perlmutter said. The simple fix: Always wear a helmet when biking, skateboarding, or rollerblading.


4) Sip mineral water. Silicon is a common mineral in tap and bottled water. It also chemically counteracts aluminum and is given to patients to treat acute aluminum poisoning. A 2013 study in the Journal of Alzheimer’s Disease found that drinking mineral water with silicon helped flush aluminum from the body. Check the label on your bottled water, which should list the minerals it contains.

5) Lower your cholesterol. If your cholesterol levels are high, getting them under control may reduce your risk for dementia. “In studies where large groups of people were followed for many years, people in midlife who were taking cholesterol-lowering statin drugs reduced their risk for dementia and Alzheimer’s disease by about 60 to 70 percent compared to those who weren’t taking statins for elevated cholesterol,” said Scharre. Keep your heart and head happy with these five tips to lower your cholesterol levels.

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